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tocris primary drug screen  (Tocris)


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    Structured Review

    Tocris tocris primary drug screen
    Tocris Primary Drug Screen, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tocris+primary+drug+screen/Tocriscreen+Stem+Cell+Library/pm40253509-268-175-175
    Average 93 stars, based on 7 article reviews
    tocris primary drug screen - by Bioz Stars, 2026-09
    93/100 stars

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    Related Articles

    Imaging:

    Article Title: Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies.
    Article Snippet: .. Cells Communications Medicine | (2025) 5:129 3 base of well nucleus cilium cytoplasm a imaging planes +1 m -5 m -6 m merge find nuclei find cytoplasm exclude border objects find spots decrease in cell number zcell normal phenotype increase in cilia number zcilia b c 50 μm 0 1000 2000 3000 4000 5000 6000 0 10 20 30 40 50 60 70 -60 -40 -20 0 20 40 siP lk1siS cr mo ck siI ft8 8 siR pg rip 1l siP lk1siS cr mo ck siI ft8 8 siR pg rip 1l -25 -20 -15 -10 -5 0 5 mean cell number mean robust z score: cell number mean percentage cells with single cilium mean robust z score: percentage cells with single cilium z c el l z c ili a Tocris primary drug screen: siP lk1siS cr mo ck siI ft8 8 siR pg rip 1l siP lk1siS cr mo ck siI ft8 8 siR pg rip 1l mock siPlk1 siScr siIft88 siRpgrip1l m er ge AR L1 3B fasudil d 50 μm Tocris primary drug screen:e Fig. 1 | High-content imaging protocol for high-throughput ciliogenesis screening. a Schematic of a polarisedmIMCD3 cell showing the focal planes used to image nuclei (blue), cytoplasm (pink) and ciliary axonemes (green). b Robust z scores were calculated to identify significant changes in cilia incidence (zcilia) or in cell number (zcell). cmIMCD3 cells imaged using anOperetta high-content imaging system.Merge images show staining for ciliamarker ARL13B (green), nuclei (DAPI; blue) and cellular RNA (TOTO-3; pink). ..

    Staining:

    Article Title: Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies.
    Article Snippet: .. Cells Communications Medicine | (2025) 5:129 3 base of well nucleus cilium cytoplasm a imaging planes +1 m -5 m -6 m merge find nuclei find cytoplasm exclude border objects find spots decrease in cell number zcell normal phenotype increase in cilia number zcilia b c 50 μm 0 1000 2000 3000 4000 5000 6000 0 10 20 30 40 50 60 70 -60 -40 -20 0 20 40 siP lk1siS cr mo ck siI ft8 8 siR pg rip 1l siP lk1siS cr mo ck siI ft8 8 siR pg rip 1l -25 -20 -15 -10 -5 0 5 mean cell number mean robust z score: cell number mean percentage cells with single cilium mean robust z score: percentage cells with single cilium z c el l z c ili a Tocris primary drug screen: siP lk1siS cr mo ck siI ft8 8 siR pg rip 1l siP lk1siS cr mo ck siI ft8 8 siR pg rip 1l mock siPlk1 siScr siIft88 siRpgrip1l m er ge AR L1 3B fasudil d 50 μm Tocris primary drug screen:e Fig. 1 | High-content imaging protocol for high-throughput ciliogenesis screening. a Schematic of a polarisedmIMCD3 cell showing the focal planes used to image nuclei (blue), cytoplasm (pink) and ciliary axonemes (green). b Robust z scores were calculated to identify significant changes in cilia incidence (zcilia) or in cell number (zcell). cmIMCD3 cells imaged using anOperetta high-content imaging system.Merge images show staining for ciliamarker ARL13B (green), nuclei (DAPI; blue) and cellular RNA (TOTO-3; pink). ..



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    93
    Tocris tocris primary drug screen
    Tocris Primary Drug Screen, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tocris+primary+drug+screen/Tocriscreen+Stem+Cell+Library/pm40253509-268-175-175
    Average 93 stars, based on 1 article reviews
    tocris primary drug screen - by Bioz Stars, 2026-09
    93/100 stars
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